After having various small issues (peroneal tendinitis) resulting from wearing stability shoes, a physical therapist suggested that I go more minimal and reduce the shoe drop. My feet pronate, but my arches are not flat. The transition was gradual. I was running in Brooks Adrenaline (too much stability) and changed to Brooks Cascadias (10 mm drop, too high). I ran a road marathon in the Cascadias without difficulty, not caring that they were trail shoes. I transitioned to Brooks Launch, then a New Balance trail shoe with an 7-8 mm drop that made a hilariously annoying squeaking noise from an exterior plastic rock plate, and these shoes demonstrated the durability of a raspberry in a panini press. The next shoe in the transition was a Pearl Izumi N2 Trail. Excellent shoes, but too narrow because after 300 miles, my left foot (which is wider than the right foot) had developed a full blast Morton's Neuroma. A quick and desperate transition to the Altra Lone Peak 2.0s allowed me to keep running with the neuroma, and I added metatarsal pads to the insoles to help split apart the 3rd and 4th metatarsal heads.
One hundred miles of trail running in the Lone Peaks, and the front part of the soles was getting worn flat and several lugs had broken off. I emailed Altra with photos of the soles, mentioning that the durability of the shoes is cause for concern.
Altra Lone Peak 2.0, with 100 trail miles
Thus, I'm going to try a pair of shoes from Topo Athletic next - the Runventures. Same wide forefoot as the Altras, but the soles look more rugged and the stack height is similar. I'd like to see how the Topos compare to the Altras with a real life test.
Transitioning to zero drop has resulted in some very sore calves, but I am optimistic that my legs and hips will eventually adjust. Running with a splayed toe/forefoot has been very comfortable. I hope other shoe manufacturers decide to capture this market.
Update: Topo Athletic sent me this useful site via Twitter to improve your stability and correct weaknesses: ACU-Running